Lock in great rates when you book your rental car at our Des Moines airport or neighborhood locations. Book now to secure your ride with Enterprise! Take in all the great sights that Iowa has to offer with a rental car from Enterprise Rent-A-Car. Choose from one of our popular airport locations or find the perfect car at a neighborhood branch. Search for a car rental location or browse the list below. Get reviews, hours, directions, coupons and more for Enterprise Rent-A-Car. Search for other Van Rental & Leasing on The Real Yellow Pages®. Rent a car in Des Moines with Enterprise. Enjoy convenient locations, great rates, and a wide selection of vehicles for business trips, weekend travel, and everyday needs. Enterprise Rent-A-Car at 2540 Leland Avenue, Des Moines, IA 50321. Get Enterprise Rent-A-Car can be contacted at (844) 996-0646. Get Enterprise Rent-A-Car reviews, rating, hours, phone number, directions and more. Enterprise Rent-A-Car is an American car rental agency headquartered in Clayton, Missouri, in Greater St. Louis. Enterprise is the flagship brand of Enterprise Holdings, which also owns other agencies including Alamo Rent a Car and National Car Rental. Enjoy fast and easy car rental bookings from Enterprise Rent-A-Car at one of our 7,200 branches in cities, airports and neighborhoods near you. Enterprise Rent-A-Car is Here For It. Whether your car is in the shop, you're running errands, or planning a weekend getaway, we're ready with a wide range of vehicles and flexible rental options. Best price car & van hire from Enterprise Rent-A Car. Get free pick up, great customer service and no hidden costs. Save up to 15% when you prepay online. About the Business Need a rental car in Des Moines, IA? Enterprise Rent-A-Car is Here For It. Whether your car is in the shop, you're running errands, or planning a weekend getaway, we're ready with a wide range of vehicles and flexible rental options. Enjoy easy, stress-free rentals and friendly service that gets yo…….